CD58 monoclonal antibody, clone MEM-63 (PE)
产品名称： CD58 monoclonal antibody, clone MEM-63 (PE)
英文名称： CD58 monoclonal antibody, clone MEM-63 (PE)
产品编号： MAB5007
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD58.
- Immunogen:
- Native purified CD58 from NALM-6 human pre-B cell line.
- Host:
- Mouse
- Theoretical MW (kDa):
- 40-70
- Reactivity:
- Human, Pig
- Specificity:
- This antibody reacts with CD58 (LFA-3), a 40-70 KDa glycoprotein distributed over many tissues, leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts.
- Form:
- Liquid
- Conjugation:
- PE
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Investigation on correlation between expression of CD58 molecule and severity of hepatitis B.
Sheng L, Li J, Qi BT, Ji YQ, Meng ZJ, Xie M.World J Gastroenterol. 2006 Jul 14;12(26):4237-40.
- 2.
- Distinct membrane localization and kinase association of the two isoforms of CD58.
Ariel O, Kukulansky T, Raz N, Hollander N.Cell Signal. 2004 Jun;16(6):667-73.
- 3.
- Expression of CD58 in normal, regenerating and leukemic bone marrow B cells: implications for the detection of minimal residual disease in acute lymphocytic leukemia.
Veltroni M, De Zen L, Sanzari MC, Maglia O, Dworzak MN, Ratei R, Biondi A, Basso G, Gaipa G.Haematologica. 2003 Nov;88(11):1245-52.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 965
- Gene Name:
- CD58
- Gene Alias:
- LFA-3,LFA3
- Gene Description:
- CD58 molecule
- Omim ID:
- 153420
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq
- Other Designations:
- CD58 antigen, (lymphocyte function-associated antigen 3),OTTHUMP00000024363
- Gene Pathway