EPHA5 polyclonal antibody
产品名称： EPHA5 polyclonal antibody
英文名称： EPHA5 polyclonal antibody
产品编号： PAB3009
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of EPHA5.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human EPHA5.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Expression profiling of the ovarian surface kinome reveals candidate genes for early neoplastic changes.
Pejovic T, Pande NT, Mori M, Mhawech-Fauceglia P, Harrington C, Mongoue-Tchokote S, Dim D, Andrews C, Beck A, Tarumi Y, Djilas J, Cappuccini F, Caballero O, Huang J, Levy S, Tsiamouri A, Cain J, Bagby GC, Strausberg RL, Simpson AJ, Odunsi KO.Transl Oncol. 2009 Dec;2(4):341-9.
- 2.
- cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.
Fox GM, Holst PL, Chute HT, Lindberg RA, Janssen AM, Basu R, Welcher AA.Oncogene. 1995 Mar 2;10(5):897-905.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of EPHA5 polyclonal antibody (Cat # PAB3009) in mouse brain tissue. EPHA5 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human brain tissue reacted with EPHA5 polyclonal antibody (Cat # PAB3009) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 2044
- Protein Accession#:
- P54756
- Gene Name:
- EPHA5
- Gene Alias:
- CEK7,EHK1,HEK7,TYRO4
- Gene Description:
- EPH receptor A5
- Omim ID:
- 600004
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Two transcript variants encoding different isoforms have been found for this gene.
- Other Designations:
- Eph homology kinase-1,ephrin receptor EphA5,ephrin type-A receptor 5,receptor protein-tyrosine kinase HEK7,tyrosine-protein kinase receptor EHK-1
- Gene Pathway
- Related Disease